Abstract
PREVIOUS studies have revealed that rabbit spleen contains unidentified, water-soluble substances that are growth stimulatory for Escherichia coli1, and also that beef spleen yields heat-resistant, water-soluble extractives stimulatory for species of pathogenic fungi2. A blood agar medium incorporating aqueous spleen infusion was formulated for the isolation of pathogenic fungi at 37° C.2. The stimulatory effects of spleen extracts on the growth of micro-organisms in chemically defined culture media has been investigated by us.
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Stapleton, G. E., Sbarra, A. J., and Hollaender, A., J. Bact., 70, 7 (1955).
Littman, M. L., Amer. J. Clin. Path., 25, 1148 (1955).
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LITTMAN, M., PISANO, M. Microbial Growth Stimulants in Spleen. Nature 181, 285 (1958). https://doi.org/10.1038/181285a0
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DOI: https://doi.org/10.1038/181285a0
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