Abstract
Vennes, MacDonald and Gerhardt1 have performed a useful service by pointing out again the potentially misleading effect of comparing serological titres expressed as actual dilutions, and their suggestion that logarithms to the base 2 (or a smaller base for finer work) should be used instead is a good one. I have earlier2 used powers of 10 in reporting titres obtained by diluting one reagent successively 1 : 10 and, by giving tube numbers3 merely, what amounted to logarithms to the base 1.5 when dilutions were made in these steps.
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References
Vennes, J. W., MacDonald, R. E., and Gerhardt, P., Nature, 180, 1363 (1957).
Hooker, S. B., and Boyd, W. C., J. Immunol., 23, 465 (1932); 24, 141 (1933).
Boyd, W. C., J. Exp. Med., 74, 369 (1941).
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BOYD, W. Use of Logarithms in recording Serological Reactions. Nature 181, 1348 (1958). https://doi.org/10.1038/1811348a0
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DOI: https://doi.org/10.1038/1811348a0
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