Abstract
THE adaptation of mammalian cells to serum-free media in tissue culture has been a subject of considerable interest in recent years. Cells grown in such media would be free from the effects of serum antibodies and other serum inhibitors of micro-organisms, and, therefore, should be suitable for long-term studies of intracellular bacteria as well as rickettsia and viruses. Such cells might also be useful in nutritional studies in tissue culture and in evaluating the effects of heterologous sera on cells in culture.
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RABSON, A., LEGALLAIS, F. & BARON, S. Adaptation to Serum-free Medium by a Phagocytic Cell Strain derived from a Marine Lymphoma. Nature 181, 1343 (1958). https://doi.org/10.1038/1811343a0
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DOI: https://doi.org/10.1038/1811343a0
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