Abstract
THE existence of γ-amino-butyric acid in the brain tissue was confirmed by Awapara1, and Roberts and Frankel2,3, and it has been identified as an active principle in the inhibitory substance that can be extracted from the mammalian brain4. Its occurrence in ocular tissue has not hitherto been established. The retina, however, can be considered anatomically to be a part of the brain, and from this point of view the retina, choroid, iris and cilliary body have been examined for the presence of γ-amino-butyric acid.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Awapara, J., Landua, A. J., Fuerst, R., and Seale, B., J. Biol. Chem., 187, 35 (1950).
Roberts, E., and Frankel, S., Fed. Proc., 9, 219 (1950).
Roberts, E., and Frankel, S., J. Biol. Chem., 187, 55 (1950).
Florey, E., Arch. Inter. Physiol., 62, 33 (1954).
Sanger, F., Biochem. J., 39, 507 (1945); 45, 563 (1949).
Koch, G., and Weidel, W., Z. physiol. Chem., 303, 213 (1956).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
KOJIMA, K., MIZUNO, K. & MIYAZAKI, M. Gamma-Amino-Butync Acid in Ocular Tissue. Nature 181, 1200–1201 (1958). https://doi.org/10.1038/1811200a0
Issue Date:
DOI: https://doi.org/10.1038/1811200a0
This article is cited by
-
Light evoked release of radioactivity from rabbit retinas preloaded with (3H)-GABA
Experientia (1977)
-
Autoradiographic Localization of 3H-GABA in Rat Retina
Nature New Biology (1972)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.