Letter | Published:

Effect of Chymotrypsin on Cæruloplasmin


INTEREST has been shown in the blue, copper-containing, serum oxidase cæruloplasmin, in particular because of its absence from the blood of subjects with hepatolenticular degeneration1. The copper of cæruloplasmin is firmly bound, being non-dialysable at neutral pH2. As part of a study of the mode of linkage of copper to the apo-enzyme, the effect of chymotryptic digestion on cæruloplasmin was investigated.

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    Kominz, D. R. (personal communication).

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