Abstract
THE conversion of serine to glycine in animal tissues was first demonstrated by Shemin1 by a feeding experiment using serine labelled with nitrogen-15 and carbon-13 in the carboxyl group. The involvement of a folic acid derivative as a co-factor in the reaction was shown both by Kisliuk and Sakami2 and Blakley3.
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References
Shemin, D., J. Biol. Chem., 162, 297 (1946).
Kisliuk, R. L., and Sakami, W., J. Amer. Chem. Soc., 76, 1456 (1954).
Blakley, R. L., Nature, 173, 729 (1954).
Tolbert, N. E., and Cohan, M. S., J. Biol. Chem., 204, 649 (1953).
Sakami, W., J. Biol. Chem., 178, 519 (1949).
Tolbert, N. E., J. Biol. Chem., 215, 27 (1955).
Blakley, R. L., Biochem. J., 65, 331 (1957).
Wright, B., and Stadtman, T. C., J. Biol. Chem., 219, 863 (1956).
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WILKINSON, A., DAVIES, D. Serine–Glycine Interconversion in Plant Tissues. Nature 181, 1070–1071 (1958). https://doi.org/10.1038/1811070a0
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DOI: https://doi.org/10.1038/1811070a0
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