Letter | Published:

Effect of Ultra-Violet Irradiation on Electrophoretic Properties of Serum Protein


IN the course of an investigation of the complement and antibody activities of animal sera (to be reported elsewhere) the effect of several agents on the serum protein has been examined by paper electrophoresis. It has recently been demonstrated that while controlled heat modified in various ways the electrophoretic pattern of serum protein it also affected differently the reactiveness of the serum with complement1. It has also been reported2 that ultra-violet irradiation of immune serum would either impair or completely destroy the ability to lyse, to agglutinate, to combine with toxins, to precipitate, to fix complement, or to confer passive anaphylaxis.

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  1. 1

    Larin, N. M., Nature, 178, 1243 (1956).

  2. 2

    Battisto, J. R., Pringle, R. B., and Nungester, W. I., J. Infect. Dis., 92, 85 (1953).

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