Abstract
RECENTLY, Griffin, Rinfret and Corsigilia1 reported that development of hepatic tumours in rats fed on a diet containing 0.06 per cent 3′-methyl-4-dimethyl-aminoazobenzene may be effectively inhibited by hypophysectomy. Chlorpromazine is a phenothiazine derivative, which is used medicinally as a potent depressant for the interbrain. Aron, Guelfi and Voisin2 reported an atonic effect of this drug on the sensibility of the pituitary gland induced by stress.
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References
Griffin, A. C., Rinfret, A. P., and Corsigilia, V. P., Cancer Research, 13, 77 (1953).
Aron, E., Guelfi, J., and Voisin, A., C.R. Soc. Biol., 149, 891 (1955).
Peters, K., Gärtner, H., and Krais, W., Strahlentherapie, 97/4, 579 (1955).
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FUJITA, K., IWASE, S., ITO, T. et al. Inhibiting Effect of Chlorpromazine on the Experimental Production of Liver Cancer. Nature 181, 54 (1958). https://doi.org/10.1038/181054a0
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DOI: https://doi.org/10.1038/181054a0
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