Letter | Published:

Lipotropic Action of Ethyl Trichloracetate

Nature volume 180, pages 859860 (26 October 1957) | Download Citation



DURING a study of the biological effects of halogen derivatives of aliphatic acids, the effects of ethyl monochloracetate and ethyl trichloracetate on rat liver have been compared. Ethyl monochloracetate has a toxic effect on liver, whereas equimolecular doses of ethyl trichloracetate cause no apparent change. However, when ethyl trichloracetate is given subcutaneously to choline-deficient rats, the high level of liver lipid is significantly reduced.

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    , , , and , Biochem. J., 52, 79 (1952).

  2. 2.

    , Anat. Rec., 106, 61 (1950).

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  1. Department of Physiology, University of Queensland, Brisbane.

    • C. C. KRATZING
  2. Department of Pathology, Brisbane Hospital, Brisbane. May 13.

    • G. M. WINDRUM


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