Letter | Published:

Xanthine Oxidase Activity during Mammary Carcinogenesis in Mice

Nature volume 180, pages 763764 (12 October 1957) | Download Citation

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Abstract

SOME hypothetical and empirical considerations that form the basis of our interest in xanthine oxidase have been stated in the first of a series of publications1. The investigations of the chemical properties of xanthine oxidase1–3 have been extended to include the biological behaviour of this enzyme in normal and abnormal growth. The present communication deals with the xanthine oxidase activity in mammæ of mice of the C strain, with and without the milk factor, and in spontaneous mammary tumours. The studies of the enzyme activity in mammæ during pregnancy and lactation will be reported elsewhere.

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Author information

Author notes

    • I. LEWIN

    Fellow in Cancer Research of the American Cancer Society. Present address: Montefiore Hospital, Division of Neoplastic Diseases, New York 67.

Affiliations

  1. Chester Beatty Research Institute, Institute of Cancer Research: Royal Cancer Hospital, Fulham Road, London, S.W.3.

    • I. LEWIN
    • , R. LEWIN
    •  & R. C. BRAY

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DOI

https://doi.org/10.1038/180763a0

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