Letter | Published:

A ‘New’ Kell Blood-Group Phenotype

Naturevolume 180page711 (1957) | Download Citation



DURING the past year or more, Dr. Fred H. Allen, jun.1,2, of the Blood Grouping Laboratory, Boston, has opened up the Kell blood-group system through the discovery of two antibodies additional to anti-K and anti-k, called anti-Kpa and anti-Kpb, which unquestionably define antigens in the Kell system. The former, he tells us, reacts with about two per cent of random bloods, while the latter reacted with all but 2 of 5,500. All bloods tested reacted with at least anti-K or anti-k and one of the new antibodies. In order to facilitate further investigation of the Kell system, Dr. Allen supplied certain laboratories, of which ours was one, with samples of these two antibodies. Having these to hand allowed us recently to define a new Kell phenotype, namely, K–, k–, Kp(a–b–), in two sisters. The Kell phenotypes of the family are as follows :

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  1. 1

    Allen, jun., Fred H., Proc. Sixth Cong. Internat. Soc. Blood Trans., Boston, U.S.A. (1956).

  2. 2

    Allen, jun., Fred H., and Lewis, Sheila J., Vox Sang. (in the press).

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  1. Rh Laboratory, 735 Notre Dame Avenue, Winnipeg, 3, Canada



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