Letter | Published:

Attempt to transplant the Œdema Fluid of Experimental Inflammatory Œdema in Rats

Nature volume 180, pages 710711 (05 October 1957) | Download Citation

Subjects

Abstract

According to the literature, the materials suspected of being either the cause of, or an important participant in, the different types of acute experimental inflammatory œdema in animals include histamine, hydroxytryptamine, some peptides (for example, leukotaxine, etc., of Menkin1), spreading factors (for example, Duran-Reynals2, McGovern3), the plasma protein permeability factor of Miles and Wilhelm4, and also certain nucleic acid derivatives (Spector and Willoughby5). The presence of at least the first two important members of these substances in œdema induced by testicular extract of the rat's hind-paw was demonstrated by Rowley and Benditt6 as well as in our laboratory. The histamine activity, for example, ranges from 2 to 10 µgm. in 1 ml. of œdema fluid.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , Science, 123, 527 (1956).

  2. 2.

    , Ann. N.Y. Acad. Sci., 52, 943 (1950).

  3. 3.

    , J. Path. Bact., 71, 1 (1956).

  4. 4.

    , and , Brit. J. Exp. Path., 36, 71 and 82 (1955).

  5. 5.

    , and , J. Path. Bact., 73, 133 (1957).

  6. 6.

    , and , Science, 123, 24 (1956).

  7. 7.

    , Acta Med. Hungarica, 9, 125 (1956).

Download references

Author information

Affiliations

  1. I. Belgyógyászati Clinic, Szeged, Hungary. April 11.

    • E. KELEMEN

Authors

  1. Search for E. KELEMEN in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/180710a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.