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A Diurnal Cycle in the Mitotic Activity of Ascites Tumour Cells in Mice

Abstract

OBSERVATIONS of a diurnal variation of frequency of mitosis in the normal tissues of the mouse show a diphasic rhythm in the skin epidermis and epithelia of oesophagus, epididymis and duodenal mucosa1. On the other hand, absence of a diurnal variation was noted in lymph nodes of the gut and in the semen-producing canals of the testis1.

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References

  1. Bullough, W. S., Proc. Roy. Soc., B, 135, 212 (1948).

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  2. Voutilainen, A., Acta Path. Microbiol. Scand., Supp., 91 (1953).

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AGRELL, I., WELIN-BERGER, E. A Diurnal Cycle in the Mitotic Activity of Ascites Tumour Cells in Mice. Nature 180, 705–706 (1957). https://doi.org/10.1038/180705b0

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