Letter | Published:

Duration of Spermatogenesis in the Mouse

Naturevolume 180page1497 (1957) | Download Citation



I AM glad that the major points of my communication1 apparently have been accepted by Sirlin and Edwards2, and especially that they now state “that preleptotene spermatocytes were initially labelled by adenine” instead of their original statement3 that “The initial labelling of deoxyribonucleic acid with adenine takes place only in spermatogonia…”. Thus the labelling is now placed at the initiation of meiosis. This confusion is another example of the result of misclassification of the products of the fifth spermatogonial division as spermatogonia. As emphasized in my communication1, such errors in classification can be avoided by using the techniques developed by Leblond and Clermont4 and extended by me to the mouse5.

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  1. 1

    Oakberg, E. F., Nature, 180, 1137 (1957).

  2. 2

    Sirlin, J. L., and Edwards, R. G., Nature, 180, 1138 (1957).

  3. 3

    Sirlin, J. L., and Edwards, R. G., Nature, 179, 725 (1957).

  4. 4

    Leblond, C. P., and Clermont, Y., Amer. J. Anat., 90, 167 (1952).

  5. 5

    Oakberg, E. F., Amer. J. Anat., 99, 391 (1956).

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  1. Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee

    • E. F. OAKBERG


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