Letter | Published:

Loss of Immunizing Power of Staphylococcal Toxin during Routine Toxoiding with Formalin

Naturevolume 180pages14791480 (1957) | Download Citation

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Abstract

IN order to render staphylococcal toxic supernatants safe for use as active immunizing agents, it is customary to incubate them with formalin, in concentrations of 0.3–0.8 per cent at temperatures between 37° and 40° C. for periods of up to two weeks1,2.

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References

  1. 1

    Dolman, C. E., J. Amer. Med. Assoc., 100, 1007 (1933).

  2. 2

    Rouyer, M., Pillett, J., Orta, B., and Nicol, M. J., Ann. Inst. Pasteur, 92, 276 (1957).

  3. 3

    Boake, W. C., J. Immunol., 76, 89 (1956).

  4. 4

    Burnet, F. M., J. Path. and Bact., 34, 471 (1931).

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    • STEPHEN FISHER

    Present address: Department of Pathology, Repatriation General Hospital, Greenslopes, Brisbane

Affiliations

  1. Commonwealth Serum Laboratories, Parkville, N.2, Victoria, Australia

    • STEPHEN FISHER

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https://doi.org/10.1038/1801479b0

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