Letter | Published:

Loss of Immunizing Power of Staphylococcal Toxin during Routine Toxoiding with Formalin

Nature volume 180, pages 14791480 (28 December 1957) | Download Citation

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Abstract

IN order to render staphylococcal toxic supernatants safe for use as active immunizing agents, it is customary to incubate them with formalin, in concentrations of 0.3–0.8 per cent at temperatures between 37° and 40° C. for periods of up to two weeks1,2.

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References

  1. 1.

    , J. Amer. Med. Assoc., 100, 1007 (1933).

  2. 2.

    , , , and , Ann. Inst. Pasteur, 92, 276 (1957).

  3. 3.

    , J. Immunol., 76, 89 (1956).

  4. 4.

    , J. Path. and Bact., 34, 471 (1931).

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Author notes

    • STEPHEN FISHER

    Present address: Department of Pathology, Repatriation General Hospital, Greenslopes, Brisbane.

Affiliations

  1. Commonwealth Serum Laboratories, Parkville, N.2, Victoria, Australia. Aug. 9.

    • STEPHEN FISHER

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DOI

https://doi.org/10.1038/1801479b0

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