Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Isotopic Tracer Method for measurement of Iron Lost into and re-absorbed from Gastro-intestinal Bleeding Lesions

Nature volume 180, pages 1278–1279 (1957)Cite this article

Abstract

IT has been shown1,2, with the help of rabbit and sheep erythrocytes labelled with iron-59, that appreciable amounts of iron from hæmoglobin were absorbed when these cells were administered orally to human beings. So far as we know, no information is available on the re-absorption of hæm-attached iron from intestinal bleeding lesions. A method for measuring such a re-absorption is here proposed.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Callender, S. T., Mallett, B. J., and Smith, M. D., Brit. J. Hæmatol., 3, 186 (1957).

    Article  CAS  Google Scholar 

  2. Walsh, R. J., Kaldor, I., Brading, I., and George, E. P., Aust. Ann. Med., 4, 272 (1955) (cited by Callender, ref. 1).

    CAS  PubMed  Google Scholar 

  3. Sterling, K., and Gray, S. J., J. Clin. Invest., 29, 1614 (1950).

    Article  CAS  Google Scholar 

  4. Roche, M., Perez-Gimenez, M. E., Layrisse, M., and Di Prisco, E., J. Clin. Invest. (July 1957).

  5. Hine, G. J., Burrows, B. A., Apt, L., Pollycove, M., Ross, J. F., and Sarkes, L. A., Nucleonics, 13, 23 (1955).

    CAS  Google Scholar 

  6. Bernhart, F. W., and Skeggs, L., J. Biol. Chem., 147, 19 (1943).

    CAS  Google Scholar 

  7. Owen, jun., C. A., Bollman, J. L., and Grindlay, J. H., J. Lab. and Clin. Med., 44, 238 (1954).

    CAS  Google Scholar 

  8. Moore, C. V., and Dubach, R., in “Modern Trends in Blood Disease” (Butterworth and Co., Ltd.. London, 1955).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Instituto de Investigaciones Médicas, Fundación Luis Roche, Plaza Morelos, Caracas, Venezuela

    M. ROCHE, M. E. PEREZ-GIMENEZ & A. LEVY

Authors
  1. M. ROCHE
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. E. PEREZ-GIMENEZ
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. LEVY
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

ROCHE, M., PEREZ-GIMENEZ, M. & LEVY, A. Isotopic Tracer Method for measurement of Iron Lost into and re-absorbed from Gastro-intestinal Bleeding Lesions. Nature 180, 1278–1279 (1957). https://doi.org/10.1038/1801278b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/1801278b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing