Enzymatic Synthesis of N-Glucuronic Acid Conjugates


RECENT investigations have shown that the formation of glucosiduronic acids can be catalysed by cell-free preparations of mammalian liver with uridine diphosphate glucuronic acid acting as the glucuronic acid donor1. These preparations have been found to synthesize ether- as well as ester-type glucuronic acid conjugates2. We wish to report the enzymatic synthesis of another type of conjugate in which glucuronic acid is linked to nitrogen.

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AXELROD, J., INSCOE, J. & TOMKINS, G. Enzymatic Synthesis of N-Glucuronic Acid Conjugates. Nature 179, 538–539 (1957) doi:10.1038/179538a0

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