Effect of the Growth Hormone of the Anterior Lobe of the Pituitary on the Reticulo-Endothelial System

Abstract

MOON et al. 1–3 found that prolonged administration of growth hormone to rats results in more neoplasms arising in the pulmonary and lymphatic tissues, adrenal glands and reproductive organs than would be expected to occur spontaneously. They also showed that hypophysectomy prevents the development of spontaneous and growth hormone-induced tumours4 and effectively inhibits the carcinogenic effect of methyl cholanthrene5.

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SNELL, R., NICOL, T. Effect of the Growth Hormone of the Anterior Lobe of the Pituitary on the Reticulo-Endothelial System. Nature 179, 473 (1957). https://doi.org/10.1038/179473a0

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