Abstract
REPORTS of total adrenalectomy in the rabbit are indeed few in number1. In general, bilateral adrenalectomy in this species has been accomplished in two stages and has been attended by high mortality. We have been impressed by the desire of many investigators to utilize the totally adrenalectomized rabbit in experimental studies and with the fact that this desire has often been frustrated because of technical difficulties following one-stage adrenalectomy. Most workers are able to remove the left adrenal with ease, but attempts to excise the right adrenal gland, even at the hands of a skilled surgeon, often result in fatal hæmorrhage from the vena cava. This occurs because the capsule of the right adrenal is connected to the adventitia of the inferior vena cava in this species.
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References
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ZAK, S., GOOD, R. & GOOD, R. A Technique for One-Stage Bilateral Adrenalectomy in the Rabbit. Nature 179, 100–102 (1957). https://doi.org/10.1038/179100b0
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DOI: https://doi.org/10.1038/179100b0
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