Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Glucuronic Acid, a Precursor of Ascorbic Acid in Aspergillus niger

Abstract

THE isotopic work of Jackel, Mosbach, Burns and King1 with rats, and that of Sivarama Sastry and Sarma2 with plants, showed definitely that in both these species, glucose is the direct precursor of L-ascorbic acid. The studies of Horowitz and King3 and Isherwood, Chen and Mapson4 have established that in both cases glucuronic acid is an intermediate in the conversion of glucose to ascorbic acid, which takes place according to the sequence:

This is a preview of subscription content

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Jackel, S. S., Mosbach, E. H., Burns, J. J., and King, C. G., J. Biol. Chem., 186, 569 (1950).

    CAS  PubMed  Google Scholar 

  2. 2

    Sivarama Sastry, K., and Sarma, P. S., Biochem. J., 62, 451 (1956).

    Article  Google Scholar 

  3. 3

    Horowitz, H. H., and King, C. G., J. Biol. Chem., 205, 815 (1954).

    Google Scholar 

  4. 4

    Isherwood, F. A., Chen, Y. T., and Mapson, L. W., Biochem. J., 56, 1 (1954).

    CAS  Article  Google Scholar 

  5. 5

    Geiger-Huber, Max, and Galli, Heidi, Verhandl. Naturforsch. Ges. Basel, 56, Pt. I, 37 (1944–45).

    Google Scholar 

  6. 6

    Butkevitch, V. S., Menshinskaja, E. V., and Trofimova, E. I., C.R. Acad. Sci. U.R.S.S., 18, No. 9, 659 (1938).

    Google Scholar 

  7. 7

    Sivarama Sastry, K., M.Sc. thesis submitted to University of Madras, Jan. 1955.

  8. 8

    Walker, T. K., “Adv. Enzymol.”, 9, 537 (1949).

    CAS  Google Scholar 

Download references

Author information

Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

SASTRY, K., SARMA, P. Glucuronic Acid, a Precursor of Ascorbic Acid in Aspergillus niger. Nature 179, 44–45 (1957). https://doi.org/10.1038/179044a0

Download citation

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links