Proteolytic Enzymes in Entamoeba histolytica


THE presence of proteolytic enzymes in Entamoeba histolytica has been suspected for many years and the extracellular secretion of these enzymes has been put forward by many authors as an explanation of the mechanism of tissue invasion by this parasite1. Experimental evidence of their occurrence in E. histolytica has been presented by several authors2, though a detailed study of them has not been made.

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  1. 1

    Anderson, H. H., Bostock, W. L., and Johnstone, H. G., “Amebiasis” (C.C. Thomas, Illinois, 1953).

  2. 2

    Balamuth, W., and Thompson, P. E., “Comparative Studies on Amebae and Amebicides”, in “Biochemistry and Physiology of Protozoa”, 2, edit. Hunter, S. H., and Lwoff, A. (Academic Press, New York, 1955).

  3. 3

    Holter, H., and Løvtrup, S., C.R. Lab. Carlsberg, Chim., 27, 27 (1949).

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