Histamine of the Reptilian Stomach and Lung

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WRIGHT et al. 1 have demonstrated that the stomach of Testudo graeca, Tachysaurus rugosus and Tiliqua nigro-lutea secretes hydrochloric acid and some pepsin in response to large doses of histamine but is only slightly responsive to vagal stimulation. The histamine concentration of the stomach of Tiliqua nigro-lutea (closely related to Tachysaurus) was therefore investigated in November 1955. The full thickness of stomach of one lizard was cut up, after scraping off contents, and boiled in Tyrode. The concentration of histamine on titration was 75 µgm./gm., which is a high level.

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