Sodium and Potassium Content of Isolated Nuclei


IT is well known that the concentration of sodium is low and that of potassium high in the intra-cellular space of most mammalian tissues. Nevertheless, an appreciable amount of each has been found in preparations of mitochondria isolated by differential centrifugation from homogenates of various tissues, particularly liver1–4 and kidney5. The purpose of the present communication is to report on the association of sodium with another cellular component, the nucleus.

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    Allfrey, V. G., Mirsky, A. E., and Osawa, S., Nature, 176, 1042 (1955).

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