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Effect of Blocking the Reticulo-endothelial System on the Storage of Vitamin A Ester and Alcohol in the Liver of the Rat

Nature volume 177, pages 575–576 (1956)Cite this article

Abstract

VITAMIN A is absorbed through the lymphatic system mostly in the esterified form1 and is stored in the liver predominantly as ester with small amounts of the free form. Its absorption via the lymphatic route raises the question of the reticulo-endothelial system being associated with its storage mechanism in the liver. Experiments, carried out in this laboratory, consisting of intraperitoneal injection of indian ink followed by oral administration of oily solutions of vitamin A, show a marked interference in the deposition of the esterified form of the vitamin in rat liver, the free form remaining unaffected.

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Authors and Affiliations

  1. Department of Biochemistry, Indian Institute of Science, Bangalore, 3

    S. KRISHNAMURTHY & J. GANGULY

Authors
  1. S. KRISHNAMURTHY
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  2. J. GANGULY
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KRISHNAMURTHY, S., GANGULY, J. Effect of Blocking the Reticulo-endothelial System on the Storage of Vitamin A Ester and Alcohol in the Liver of the Rat. Nature 177, 575–576 (1956). https://doi.org/10.1038/177575a0

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  • DOI: https://doi.org/10.1038/177575a0

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