Abstract
THE isolation and purification of a hypertensin peptide, resulting from the action of rabbit renin on ox serum, have been described recently by one of us. Its amino-acid composition was consistent with a decapeptide structure containing the following eight amino-acids: leucine (1), phenylalanine (1), tyrosine (1), proline (1), aspartic acid (1), arginine (1), valine (2) and histidine (2). Application of the fluorodinitrobenzene technique of Sanger showed that the N-terminal residue was aspartic acid1. The amino-acid sequence in this peptide has been determined by the following methods:
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References
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ELLIOTT, D., PEART, W. Amino-Acid Sequence in a Hypertensin. Nature 177, 527–528 (1956). https://doi.org/10.1038/177527a0
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DOI: https://doi.org/10.1038/177527a0
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