Abstract
THE hæmoglobin of red cells appears to be synthesized during the early stages of maturation, and its formation is more or less complete by the time the cells leave the bone marrow. Although reticulocytes have practically their full complement of hæmoglobin, evidence from amino-acid incorporation studies1 suggests that these cells, unlike mature erythrocytes, still have protein-synthesizing capacity. In view of this, it was felt that it would be of interest to see if certain enzymes were at a high level of activity in reticulocytes ; Table 1 summarizes the results of a preliminary investigation of the level of activity in the two types of cell for a number of enzymes which might be involved in some way in a protein-synthesizing mechanism.
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ELLIS, D., SEWELL, C. & SKINNER, L. Reticulocyte Enzymes and Protein Synthesis. Nature 177, 190–191 (1956). https://doi.org/10.1038/177190b0
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DOI: https://doi.org/10.1038/177190b0
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