Abstract
IT is now a commonplace that, in culture, resistant organisms may be already present before there has been any contact between them and an antibiotic1. I demonstrated1a that this was true even in young cultures derived from single cells.
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References
(a) Hughes, W. H., J. Gen. Microbiol., 6, 175 (1952). (b) Eagle, H., Fleischmann, R., and Levy, M., J. Bact., 63, 623 (1952). (c) Collard, P., Riass. Commun. VI Cong. int. Microbiol., 1, 155 (1953). (d) Mayr-Harting, A., J. Gen. Microbiol., 13, 9 (1955).
Rowley, D., J. Gen. Microbiol., 6, 272 (1952).
Hughes, W. H., J. Gen. Microbiol., 12, 269 (1955).
Vadasz, J., and Juhasz, I., Nature, 176, 169 (1955).
Lwoff, A., and Gutmann, A., Ann. Inst. Pasteur, 78, 711 (1950).
Crawley, N., and Jevons, M. P., J. Gen. Microbiol., 13, 226 (1955).
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HUGHES, W. Bacterial Variation to Sensitivity : an Example of Individuality in Micro-organisms. Nature 177, 1132–1133 (1956). https://doi.org/10.1038/1771132a0
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DOI: https://doi.org/10.1038/1771132a0
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