Letter | Published:

Effect of Deoxycorticosterone on the Reticulo-Endothelial System

Abstract

THE reticulo-endothelial system is known to be an important defence mechanism against malignant growths in general1. Nicol, Helmy and Abou-Zikry2 showed that œstrogens, especially in combination with orchidectomy, stimulate the reticulo-endothelial macrophages in the liver, spleen and lymph nodes and appear to lead to mobilization of the macrophages in these organs. It is probable that such stimulation increases the general defence of the body against tumour growth.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Kavetzki, R. E., and Diadjuscha, G. F., J. Med. Ukrain., 7, 837 (1937). Stern, K., J. Lab. Clin. Med., 26, 809 (1941).

  2. 2

    Nicol, T., Helmy, I. D., and Abou-Zikry, A., Brit. J. Surg., 40, 166 (1952).

  3. 3

    Nicol, T., and Snell, R. S., Nature, 174, 554 (1954).

  4. 4

    Pearson, O. D., Eliel, L. P., Rawson, R. W., Dobriner, K., and Rhoads, C. P., Cancer, 2, 943 (1949). Pearson, O. D., Eliel, L. P., and Talbot, jun., T. R., Bull. New York Acad. Med., 26, 235 (1950).

  5. 5

    Frada, G., Presse Méd., 58, 78 (1950).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.