Letter | Published:

Inactivation of Phage due to Assimilated Phosphorus-32 and the Recovery of Host Cells

Naturevolume 175pages992993 (1955) | Download Citation

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Abstract

FROM experiments carried out by other authors1, who have exposed to ultra-violet light and to X-rays bacteria infected with different types of phages (T2, T7), it has been possible to obtain a general picture of the changes which take place during the latent period, from infection to the lysis of the host cells. It was found, in agreement also with other types of experiments, that phage T2 begins to multiply only about 7–9 min. after infection. During this period the particle is not infectious and is responsible for the changes in the host cell which lead to the synthesis of new virus. Study of this early period might thus furnish important information about the relationships established between virus and host cell.

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References

  1. 1

    Latarjet, R., and Luria, S., Ann. Inst. Past., 73, 666 (1947). Latarjet, R., J. Gen. Physiol., 31, 529 (1948). Benzer, S., J. Bact., 63, 59 (1952).

  2. 2

    Coppo, A., N. Ann. Ig. Microbiol. (in the press).

  3. 3

    Castagnoli, C., and Graziosi, F., Nature, 174, 599 (1954).

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Affiliations

  1. Istituto di Fisica

    • C. CASTAGNOLI
  2. Istituto di Microbiologia, Università di Roma

    • P. DONINI
    •  & F. GRAZIOSI

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https://doi.org/10.1038/175992b0

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