Abstract
URETHANE injected, given by mouth, or applied to the skin, induces the formation of multiple lung adenomata in mice and rats. It also inhibits the growth of some transplanted animal tumours, and induces remissions in human leukæmia. Its many other biological effects include the induction of chromosome abnormalities and mutations.
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ROE, F. Tumour-initiating Action of Urethane and its Inhibition by Purine Precursors. Nature 175, 636–637 (1955). https://doi.org/10.1038/175636b0
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DOI: https://doi.org/10.1038/175636b0
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