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Development of Fertilizing Capacity of Rabbit Spermatozoa in the Uterus

Naturevolume 175pages10361037 (1955) | Download Citation



BY deposition of sperm into the Fallopian tubes of a rabbit at various times before or after ovulation, it has been found1 that ejaculated or epididymal spermatozoa require about six hours stay in the tubes to acquire their fertilizing capacity. Although sperm incubated in the uterus of a live animal for five hours was found to be capable of fertilization when deposited into the tube, the time requirement in the uterus was not systematically determined. The following experiment provides more direct evidence to show that spermatozoa placed in the uterus also require a definite period of time to develop their fertilizing capacity. However, attempts to develop the fertilizing capacity of ejaculated sperm in vitro have been unsuccessful.

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  1. Worcester Foundation for Experimental Biology, Shrewsbury, Mass.

    • M. C. CHANG


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