Letter | Published:

Development of Fertilizing Capacity of Rabbit Spermatozoa in the Uterus

Naturevolume 175pages10361037 (1955) | Download Citation

Subjects

Abstract

BY deposition of sperm into the Fallopian tubes of a rabbit at various times before or after ovulation, it has been found1 that ejaculated or epididymal spermatozoa require about six hours stay in the tubes to acquire their fertilizing capacity. Although sperm incubated in the uterus of a live animal for five hours was found to be capable of fertilization when deposited into the tube, the time requirement in the uterus was not systematically determined. The following experiment provides more direct evidence to show that spermatozoa placed in the uterus also require a definite period of time to develop their fertilizing capacity. However, attempts to develop the fertilizing capacity of ejaculated sperm in vitro have been unsuccessful.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Chang, M. C., Nature, 168, 697 (1951).

  2. 2

    Chang, M. C., J. Exp. Zool., 121, 351 (1952).

  3. 3

    Hammond, J., and Asdell, S. A., Brit. J. Exp. Biol., 4, 155 (1926).

  4. 4

    Hammond, J., J. Exp. Biol., 11, 140 (1934).

  5. 5

    Chang, M. C., “Mammalian Germ Cells” (Ciba Found. Symp., Churchill, London, 1953).

  6. 6

    Austin, C. R., Aust. J. Sci. Res., B, 4, 581 (1951).

  7. 7

    Austin, C. R., Nature, 170, 326 (1952).

  8. 8

    Austin, C. R., and Braden, A. W. H., Aust. J. Biol. Sci., 7, 179 (1954).

  9. 9

    Chang, M. C., and Pincus, G., Physiol. Rev., 31, 1 (1951).

  10. 10

    Smith, A. U., “The Biochemistry of Fertilization and the Gametes”, Biochem. Soc. Symp. No. 7 (1951).

  11. 11

    Dauzier, L., Thibault, C., and Wintenberger, S., C.R. Acad. Sci., Paris, 238, 844 (1954).

  12. 12

    Moricard, R., Nature, 173, 1140 (1954).

Download references

Author information

Affiliations

  1. Worcester Foundation for Experimental Biology, Shrewsbury, Mass.

    • M. C. CHANG

Authors

  1. Search for M. C. CHANG in:

About this article

Publication history

Issue Date

DOI

https://doi.org/10.1038/1751036a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.