Abstract
BY deposition of sperm into the Fallopian tubes of a rabbit at various times before or after ovulation, it has been found1 that ejaculated or epididymal spermatozoa require about six hours stay in the tubes to acquire their fertilizing capacity. Although sperm incubated in the uterus of a live animal for five hours was found to be capable of fertilization when deposited into the tube, the time requirement in the uterus was not systematically determined. The following experiment provides more direct evidence to show that spermatozoa placed in the uterus also require a definite period of time to develop their fertilizing capacity. However, attempts to develop the fertilizing capacity of ejaculated sperm in vitro have been unsuccessful.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Chang, M. C., Nature, 168, 697 (1951).
Chang, M. C., J. Exp. Zool., 121, 351 (1952).
Hammond, J., and Asdell, S. A., Brit. J. Exp. Biol., 4, 155 (1926).
Hammond, J., J. Exp. Biol., 11, 140 (1934).
Chang, M. C., “Mammalian Germ Cells” (Ciba Found. Symp., Churchill, London, 1953).
Austin, C. R., Aust. J. Sci. Res., B, 4, 581 (1951).
Austin, C. R., Nature, 170, 326 (1952).
Austin, C. R., and Braden, A. W. H., Aust. J. Biol. Sci., 7, 179 (1954).
Chang, M. C., and Pincus, G., Physiol. Rev., 31, 1 (1951).
Smith, A. U., “The Biochemistry of Fertilization and the Gametes”, Biochem. Soc. Symp. No. 7 (1951).
Dauzier, L., Thibault, C., and Wintenberger, S., C.R. Acad. Sci., Paris, 238, 844 (1954).
Moricard, R., Nature, 173, 1140 (1954).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
CHANG, M. Development of Fertilizing Capacity of Rabbit Spermatozoa in the Uterus. Nature 175, 1036–1037 (1955). https://doi.org/10.1038/1751036a0
Issue Date:
DOI: https://doi.org/10.1038/1751036a0
This article is cited by
-
Phosphodiesterase 11 (PDE11) regulation of spermatozoa physiology
International Journal of Impotence Research (2005)
-
Versuche mit Rinder- und Schweinekeimzellen zur Reifung, Befruchtung und Embryonenz�chtung in vitro
Archiv f�r Gyn�kologie (1970)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
