Abstract
Nicol, Helmy and Abou-Zikry1 showed that œstrogens stimulate the reticulo-endothelial macrophages in the spleen, liver, and lymph nodes, and that prolonged œstrogen treatment or stimulation by large doses of œstrogen appears to load to mobilization of the macrophages in these organs. The reticulo-endothelial system is an important defence mechanism against malignant tumours in general2,3, and its stimulation therefore probably increases the general defence of the body against tumour growth.
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Nicol, T., Helmy, I. D., and Abou-Zikry, A., Brit. J. Surg., 40, 166 (1952).
Kavetzki, R. E., and Diadjuscha, G. F., J. Med. Ukrain, 7, 837 (1937).
Stern, K., J. Lab. Clin. Med., 26, 809 (1941).
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NICOL, T., SNELL, R. Cortisone in Relation to Infection and Tumour Growth. Nature 174, 554 (1954). https://doi.org/10.1038/174554a0
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DOI: https://doi.org/10.1038/174554a0
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