Abstract
IN a previous communication1, we reported the discovery of the antagonism which certain substances exhibited towards morphine but not towards barbiturates. One of these substances was 2-4 diamino 5 phenyl thiazole. We wish to report now the discovery of a compound which is a barbiturate antagonist, and at the same time to link this antagonism with that of morphine by means of 2-4 diamino 5 phenyl thiazole (which has now been shown to be slightly antagonistic to barbiturates).
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References
Shaw, F. H., and Bentley, G., Nature, 169, 712 (1952).
Shaw, F. H., Shulman, A., Cass, N., and Whyte, M. H., Med. J. Aust. (in the press).
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SHAW, F., SIMON, S., CASS, N. et al. Barbiturate Antagonism. Nature 174, 402–403 (1954). https://doi.org/10.1038/174402a0
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DOI: https://doi.org/10.1038/174402a0
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