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Structure of Collagen

Abstract

A DETAILED X-ray study of collagen fibres obtained from different sources (namely, shark ray, rat tail tendon and kangaroo tail tendon) and a re-examination of the published wide-angle patterns indicate that the unit cell of collagen is hexagonal with a = 12–16 A. and c = 9.5–9 A., the actual values depending on the moisture content. The essential difference of this indexing from those reported earlier1–3 is that the 2.86-A. meridional arc is here interpreted not as a true meridional reflexion, but as arising from the superposition of two close non-meridional reflexions. A calculation of the angular spread of the arc, using the tilt of the c-axis deduced from the spread of the equatorial reflexions, confirms this interpretation. Table 1 shows the good agreement between the calculated and observed spacings of an air–dried and a wet specimen from kangaroo tail tendon.

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References

  1. Astbury, W. T., J. Int. Soc. Leather Chem., 24, 69 (1940).

    CAS  Google Scholar 

  2. Pauling, L., and Corey, R. B., Proc. U.S. Nat. Acad. Sci., 37, 272 (1951).

    Article  ADS  CAS  Google Scholar 

  3. Bear, R. S., “Advances in Protein Chemistry”, 7, 69 (1953).

    Google Scholar 

  4. Corey, R. B., and Pauling, L., Proc. Roy. Soc., B, 141, 10 (1953).

    Article  ADS  CAS  Google Scholar 

  5. Randall, J. T., Fraser, R. D. B., and North, A. C. T., Proc. Roy. Soc., B, 141, 62 (1953).

    Article  ADS  CAS  Google Scholar 

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RAMACHANDRAN, G., KARTHA, G. Structure of Collagen. Nature 174, 269–270 (1954). https://doi.org/10.1038/174269c0

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