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Constitution of Cynarine, the Active Principle of the Artichoke
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  • Published: 04 December 1954

Constitution of Cynarine, the Active Principle of the Artichoke

  • LUIGI PANIZZI1 &
  • MARIA LUISA SCARPATI1 

Nature volume 174, page 1062 (1954)Cite this article

  • 1529 Accesses

  • 44 Citations

  • 4 Altmetric

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Abstract

IT has been known for some time that the artichoke (Cynara scolymus) contains some hitherto unidentified substances which stimulate biliary secretion and cholesterinic metabolism1. The extraction of these substances can be carried out by infusion or decoction. We have been able to isolate from cauline leaves of Cynara scolymus a crystalline substance which we have also found in Cynara cardunculus. Because of its physiological activity, we have used the word ‘cynarine’, which has been generally used for the chemical principle of the artichoke with the same activity2.

References

  1. Cf. Chabrol, E., Charonnat, R., Maximin, M., and Waitz, R., C.R. Soc. Biol., 108, 1020 (1931). Tixier, L., and de Sère, S., Chem. Abstr., 7535 (1937). Tixier, L., Presse Médicale, 47, 880 (1939). Schoenholzer, G., Schwz. Med. Wschr., 69, 1288 (1939). Roffo, A. H., Bol. Inst. Med. Exp. Cancer, 20, 65 (1943). Legrand, G., C.R. Acad. Sci., Paris, 227, 600 (1948). Hermann, G. R., Chem. Abstr., 3489 (1948).

    CAS  Google Scholar 

  2. Cf. Ravina, A., Presse Médicale, 42, 1307 (1934).

    CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Istituto di Chimica Organica, Università di Roma,

    LUIGI PANIZZI & MARIA LUISA SCARPATI

Authors
  1. LUIGI PANIZZI
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  2. MARIA LUISA SCARPATI
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Cite this article

PANIZZI, L., SCARPATI, M. Constitution of Cynarine, the Active Principle of the Artichoke. Nature 174, 1062 (1954). https://doi.org/10.1038/1741062a0

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  • Issue Date: 04 December 1954

  • DOI: https://doi.org/10.1038/1741062a0

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