Abstract
WE have recently found that the decrease of ascorbic acid concentration of rats' adrenals due to epinephrine is smaller in rats to which pituitrin has been administered and in dehydrated rats than in normal rats1. This suggests that the posterior pituitary hormone depresses the adrenal cortical activity. The questions arise, whether the posterior pituitary hormone acts directly on the adrenal or indirectly through the depression of the anterior pituitary secretion, and which fraction of the posterior pituitary hormone, pressor or oxytocic, is responsible for this effect. The present work was undertaken to clarify these points.
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References
See Kimura, M., Jap. J. Physiol. [4, 24 (1954)].
Roe, J. H., and Kuether, C. A., J. Biol. Chem., 147, 399 (1943).
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ITOH, S., ARIMURA, A. Effect of Posterior Pituitary Hormone on the Release of Adrenocorticotrophic Hormone. Nature 174, 37 (1954). https://doi.org/10.1038/174037a0
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DOI: https://doi.org/10.1038/174037a0
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