Abstract
EARLIER investigations in this Institute1 have shown that substances like dyestuffs and some proteins show a very marked increase of adsorption on to filter paper and other adsorbents in presence of salts in large concentrations. The adsorption may thus be increased from practically zero (in pure water) to considerable amounts, and the phenomenon may be utilized for chromatographic separations, using salt solutions of lower concentrations or even water for the elution. Similarly, Holman and Hagdahl2 found that the adsorption of fatty acids on to carbon from solutions in ethanol was very markedly increased if the solubility was reduced by adding water to the solution.
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References
Tiselius, A., Arkiv för Kemi, 26B, No. 1 (1948).
Hagdahl, L., and Holman, R. T., J. Amer. Chem. Soc., 72, 701 (1950).
Tiselius, A., Faraday Soc. Discuss No. 7, 7 (1949). Shepard, C., and Tiselius, A., ibid., No. 7, 275 (1949).
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HAGDAHL, L., TISELIUS, A. Salting-out Chromatography of Amino-acids and Peptides in Filter Paper and other Media. Nature 170, 799–800 (1952). https://doi.org/10.1038/170799b0
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DOI: https://doi.org/10.1038/170799b0
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