Abstract
MANY enzymes contain sulphydryl groups essential to their activity; they are readily inactivated by oxidation. It is known that reduced glutathione protects them against oxidation1. In this respect hæmoglobin behaves in a similar manner to the ‘SH-enzyme’ in that its spontaneous oxidation to methæmoglobin is inhibited by glutathione2.
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References
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FEGLER, G. Relationship between Reduced Glutathione Content and Spontaneous Hæmolysis in Shed Blood. Nature 170, 624–625 (1952). https://doi.org/10.1038/170624a0
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DOI: https://doi.org/10.1038/170624a0
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