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Molluscum contagiosum infection after reduced-intensity cord blood transplantation

Bone Marrow Transplantation volume 38, pages 313–314 (2006)Cite this article

Cord blood transplantation is an attractive alternative for patients with hematologic malignancies who do not have a matched related or unrelated donor. The feasibility of cord blood transplantation using reduced-intensity regimens (reduced-intensity unrelated cord blood transplantation (RICBT)) for adult patients with hematologic diseases has been reported.1, 2 Owing to delayed immune recovery, infection is the most significant problem in RICBT as well as conventional cord blood transplantation.3, 4

Molluscum contagiosum (MC) is an infectious skin disease caused by the Molluscipoxvirus genus, which is a member of poxvirus family.5 In children, infection spreads by direct contact or sharing of fomites, with lesions predominantly on the trunk, extremities and face. In young adults, infections are transmitted through sexual intercourse. Whereas atypical clinical presentations of MC have been reported in immunocompromised patients and those with atopic dermatitis,6, 7 no reports have been published on MC following RICBT, to our knowledge.

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Authors and Affiliations

  1. Department of Hematology, Toranomon Hospital, Tokyo, Japan

    E Kusumi, S Takagi, S Miyakoshi & S Taniguchi

  2. Division of Exploratory Research, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

    E Kusumi, T Matsumura, Y Tanaka & M Kami

  3. Department of Internal Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

    K Yuji

  4. Department of Dermatology, Toranomon Hospital, Tokyo, Japan

    A Kishi

  5. Office for Life-Style Related Diseases Control, Ministry of Health, Labour and Welfare, Tokyo, Japan

    N Murashige

Authors
  1. E Kusumi
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  2. K Yuji
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  3. A Kishi
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  4. N Murashige
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  5. S Takagi
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  6. T Matsumura
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  7. Y Tanaka
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  8. S Miyakoshi
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  9. M Kami
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  10. S Taniguchi
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Correspondence to E Kusumi.

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Kusumi, E., Yuji, K., Kishi, A. et al. Molluscum contagiosum infection after reduced-intensity cord blood transplantation. Bone Marrow Transplant 38, 313–314 (2006). https://doi.org/10.1038/sj.bmt.1705428

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