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Graft-Versus-Host Disease

Intra-arterial steroid-injection therapy for steroid-refractory acute graft-versus-host disease with the evaluation of angiography

Bone Marrow Transplantation volume 33, pages 1231–1233 (2004)Cite this article

Summary:

We treated three patients with steroid-refractory acute graft-versus-host disease (aGVHD) with intra-arterial steroid-injection therapy (IAST). Two patients with gut aGVHD received IAST into both superior and inferior mesenteric arteries, while one patient with liver aGVHD received IAST into the proper hepatic artery. The volume of stools and the bilirubin level improved soon after IAST. Angiography of the superior and inferior mesenteric arteries was performed in the two patients with steroid-refractory gut aGVHD, and identical abnormal findings were obtained. IAST might be an earlier option for steroid-refractory aGVHD.

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Acknowledgements

We are grateful to Miss Tomoko Masuda for her secretarial work.

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Authors and Affiliations

  1. First Department of Internal Medicine, Kansai Medical University, Moriguchi-shi, Osaka, Japan

    K Nakai, K Tajima, N Matsumoto, K Zen, S Nomura, M Fujimoto, Y Kishimoto, R Amakawa & S Fukuhara

  2. Radiology, Kansai Medical University, Moriguchi-shi, Osaka, Japan

    N Tanigawa & S Sawada

Authors
  1. K Nakai
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  2. K Tajima
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  3. N Tanigawa
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  4. N Matsumoto
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  5. K Zen
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  6. S Nomura
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  7. M Fujimoto
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  8. Y Kishimoto
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  9. R Amakawa
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  10. S Sawada
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  11. S Fukuhara
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Correspondence to K Nakai.

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Nakai, K., Tajima, K., Tanigawa, N. et al. Intra-arterial steroid-injection therapy for steroid-refractory acute graft-versus-host disease with the evaluation of angiography. Bone Marrow Transplant 33, 1231–1233 (2004). https://doi.org/10.1038/sj.bmt.1704523

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