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Nonmyeloablative allogenic peripheral-blood stem-cell transplantation in pancreatic adenocarcinoma: one case, high expectations

Bone Marrow Transplantation volume 33, page 251 (2004)Cite this article

We read with great interest the case report by Omuro et al,1 which describes the regression of an unresectable pancreatic tumor, following nonmyeloablative allogenic peripheral-blood stem-cell transplantation. The authors hypothesize that a graft vs tumor effect might have determined the favorable clinical response.

Due to the obvious expectations that this case report might generate in those who daily face an otherwise rapidly lethal disease, we would like to call for caution while making a few comments on the specific case.

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References

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Authors and Affiliations

  1. Gastroenterology Department, Research Laboratory-Molecular Genetics, Istituto Clinico Humanitas, via Manzoni, 56, Rozzano (Mi), 20089, Italy

    L Laghi & A Malesci

  2. Oncology Department, Istituto Clinico Humanitas, Rozzano, Italy

    L Castagna

  3. Internal Medicine Department, University of Milan, Italy

    A Malesci

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  1. L Laghi
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  2. L Castagna
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  3. A Malesci
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Laghi, L., Castagna, L. & Malesci, A. Nonmyeloablative allogenic peripheral-blood stem-cell transplantation in pancreatic adenocarcinoma: one case, high expectations. Bone Marrow Transplant 33, 251 (2004). https://doi.org/10.1038/sj.bmt.1704331

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