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Progressive multifocal leukoencephalopathy after stem cell transplantation, unsuccessfully treated with cidofovir

Bone Marrow Transplantation volume 30, pages 963–966 (2002)Cite this article

Abstract

We report a patient with progressive multifocal leukoencephalopathy (PML) after autologous stem cell transplantation (SCT) for non-Hodgkin's lymphoma (NHL). This is an unusual association, and to date only seven cases have been reported. This is the first case of PML after SCT treated with cidofovir, and the fifth case treated with this drug in a patient without human immunodeficiency virus (HIV) infection. In the previous four patients treated with cidofovir the outcome was discouraging, as was the case in this patient.

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Authors and Affiliations

  1. Department of Hematology, Hospital de la Princesa, Madrid, Spain

    S Osorio, R de la Cámara, N Golbano, E Marti & JM Fernández-Rañada

  2. Department of Pathology, Hospital de la Princesa, Madrid, Spain

    S Nieto

  3. Department of Radiology, Hospital de la Princesa, Madrid, Spain

    R Manzanares

  4. Centro Nacional de Microbiología, Instituto Carlos III, Madrid, Spain

    CG Fedele

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  1. S Osorio
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  2. R de la Cámara
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  8. JM Fernández-Rañada
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Osorio, S., de la Cámara, R., Golbano, N. et al. Progressive multifocal leukoencephalopathy after stem cell transplantation, unsuccessfully treated with cidofovir. Bone Marrow Transplant 30, 963–966 (2002). https://doi.org/10.1038/sj.bmt.1703704

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  • DOI: https://doi.org/10.1038/sj.bmt.1703704

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