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Resolution of chronic idiopathic thrombocytopenia purpura following syngeneic peripheral blood progenitor transplant

Abstract

Idiopathic thrombocytopenia purpura (ITP) is an acquired disease of children and adults characterized by a low platelet count, an essentially normal bone marrow, and absence of evidence for other disease. We report the use of syngeneic peripheral blood progenitor transplantation (PBPT) in a 19-year-old male with chronic refractory ITP since the age of 5. Engraftment was successful and has resulted in resolution of his disease. We conclude that syngeneic PBPT is a potentially curative option for refractory ITP.

Bone Marrow Transplantation (2002) 29, 87–89. doi:10.1038/sj.bmt.1703336

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Zaydan, M., Turner, C. & Miller, A. Resolution of chronic idiopathic thrombocytopenia purpura following syngeneic peripheral blood progenitor transplant. Bone Marrow Transplant 29, 87–89 (2002). https://doi.org/10.1038/sj.bmt.1703336

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