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Viral Complications

Respiratory syncytial virus infection in the late bone marrow transplant period: report of three cases and review

Bone Marrow Transplantation volume 27, pages 1071–1073 (2001)Cite this article

Abstract

Respiratory syncytial virus (RSV) infection is an important cause of respiratory mortality in immunosuppressed patients, including bone marrow transplant (BMT) recipients. The presence of lower respiratory tract infection and infection in the pre-engraftment phase of BMT is believed to confer a poor prognosis. Three patients who underwent allogeneic BMT at our institution developed RSV pneumonia over 1 year post BMT, with the underlying disease in remission. All three were hypoxic with extensive pulmonary disease at presentation. Treatment consisted of aerosolized ribavirin and intravenous immune globulin with successful clearing of viral shedding and excellent clinical outcomes. RSV infection is probably less severe in the late post-BMT period, but needs to be considered early in the differential diagnosis of pulmonary infiltrates in this patient population. Bone Marrow Transplantation (2001) 27, 1071–1073.

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Authors and Affiliations

  1. Division of Medicine, Roswell Park Cancer Institute, Buffalo, NY, USA

    NI Khushalani, D Wentling, K Brown, A Mohr, B Anderson, C Keesler, D Ball, ZP Bernstein, SH Bernstein, MS Czuczman, BH Segal & PL McCarthy Jr

  2. Division of Infectious Diseases, State University of New York, Buffalo, NY, USA

    FG Bakri & BH Segal

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  1. NI Khushalani
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  2. FG Bakri
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  3. D Wentling
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  4. K Brown
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  8. D Ball
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  10. SH Bernstein
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Khushalani, N., Bakri, F., Wentling, D. et al. Respiratory syncytial virus infection in the late bone marrow transplant period: report of three cases and review. Bone Marrow Transplant 27, 1071–1073 (2001). https://doi.org/10.1038/sj.bmt.1703046

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  • DOI: https://doi.org/10.1038/sj.bmt.1703046

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