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Erythropoietin in stem cell transplantation

Bone Marrow Transplantation volume 27, pages 1011–1016 (2001)Cite this article

Abstract

Anemia is universal after allogeneic and autologous stem cell transplantation, with both increased red cell utilization and decreased production playing a role. This anemia sometimes is associated with a relative erythropoietin deficiency. In allogeneic stem cell transplantation, randomized trials have demonstrated improved erythropoiesis and a decrease in red cell transfusions in recombinant human erythropoietin (rHuEPO)-treated patients. Studies of rHuEPO in patients undergoing autologous stem cell transplants, however, have not shown a benefit. The role of rHuEPO in stem cell mobilization and treatment of delayed erythropoiesis has yet to be defined and further studies are needed. Bone Marrow Transplantation (2001) 27, 1011–1016.

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Authors and Affiliations

  1. Johns Hopkins Oncology Center, Baltimore, MD, USA

    CB Miller

  2. Department of Medicine, Ireland Cancer Centre, University Hospitals of Cleveland, Cleveland, OH, USA

    HM Lazarus

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Miller, C., Lazarus, H. Erythropoietin in stem cell transplantation. Bone Marrow Transplant 27, 1011–1016 (2001). https://doi.org/10.1038/sj.bmt.1703022

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