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Successful engraftment of a second transplant using non-myeloablative conditioning as treatment for graft failure following unrelated donor BMT

Bone Marrow Transplantation volume 27, pages 547–549 (2001)Cite this article

Abstract

A 32-year-old man with CML in second chronic phase developed primary graft failure following matched unrelated donor transplantation using cryopreserved marrow cells. He was successfully regrafted within 60 days from a second fully matched donor using a non-myeloablative conditioning regimen, with minimal toxicity. He remains in complete haematological, cytogenetic and molecular remission 2 years after second transplant. We believe that reduced intensity or ‘mini-transplants’ may be preferable for patients requiring second allografts which are usually associated with a high transplant-related mortality. Bone Marrow Transplantation (2001) 27, 547–549.

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  1. Department of Haematology, Nottingham City Hospital, Nottingham, UK

    JL Byrne, C Musuka, B Davy, L Donovan & NH Russell

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  1. JL Byrne
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  2. C Musuka
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  3. B Davy
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  4. L Donovan
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  5. NH Russell
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Byrne, J., Musuka, C., Davy, B. et al. Successful engraftment of a second transplant using non-myeloablative conditioning as treatment for graft failure following unrelated donor BMT. Bone Marrow Transplant 27, 547–549 (2001). https://doi.org/10.1038/sj.bmt.1702825

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  • DOI: https://doi.org/10.1038/sj.bmt.1702825

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