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One antigen mismatched related donor bone marrow transplant in a patient with acute lymphoblastic leukaemia and β-thalassaemia major: potential cure of both marrow disorders

Bone Marrow Transplantation volume 25, pages 677–678 (2000)Cite this article

Abstract

We report a case of a 34-year-old man with T-ALL and β-thalassaemia major who underwent a one antigen mismatched related donor bone marrow transplant. Five months post transplant chimeric studies revealed full donor haemopoiesis and the patient remains leukaemia and thalassaemia free at 12 months post transplant. Cumulative risk factors contributing to the increased transplant-related mortality in patients with two different marrow disorders are discussed. Bone Marrow Transplantation (2000) 25, 677–678.

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Authors and Affiliations

  1. Department of Haematology, University College London Hospitals, London, UK

    PD Kottaridis, K Peggs, A Lawrence, S Verfuerth, JB Porter, S Mackinnon & AH Goldstone

  2. Department of Reproductive Medicine Unit, University College London Hospitals, London, UK

    R Chatterjee

  3. Department of Haematology, Royal London Hospitals, London, UK

    P Telfer

Authors
  1. PD Kottaridis
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  2. K Peggs
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  3. A Lawrence
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  4. S Verfuerth
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  5. R Chatterjee
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  6. P Telfer
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  7. JB Porter
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  8. S Mackinnon
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  9. AH Goldstone
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Kottaridis, P., Peggs, K., Lawrence, A. et al. One antigen mismatched related donor bone marrow transplant in a patient with acute lymphoblastic leukaemia and β-thalassaemia major: potential cure of both marrow disorders. Bone Marrow Transplant 25, 677–678 (2000). https://doi.org/10.1038/sj.bmt.1702213

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  • DOI: https://doi.org/10.1038/sj.bmt.1702213

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