Abstract
THERE are few reports of rat tissue cultures producing growth comparable to that from other mammalian species or from chick explants. Martinovitch1, working with rat pituitary and rat ovary in watch-glass cultures, was able to keep the tissues alive in vitro for a considerable length of time; but cell outgrowth was comparatively slight. Abercrombie and Harkness2 cultured regenerating rat liver. Fibro-blasts or bile duct epithelium rarely grew from normal liver cultures, but appeared sporadically in cultures of regenerating material, the outgrowth varying with the state of liver regeneration. Only lymphocytes and granulocytes occurred in cultures regularly and in similar numbers regardless of the state of regeneration. The only case of rat pituitary tissue producing vigorous growth in vitro is that reported by Haymaker and Anderson3.
Similar content being viewed by others
Article PDF
References
Martinovitch, P., Proc. Roy. Soc., B, 125, 232 (1938); 128, 138 (1939).
Abercrombie, M., and Harkness, R. D., Proc. Roy. Soc., B, 138, 544 (1951).
Haymaker, W., and Anderson, E., J. Path. and Bact., 42, 399 (1936).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SCOTT, J. Growth of Rat Ovary in Tissue Culture. Nature 170, 208 (1952). https://doi.org/10.1038/170208a0
Issue Date:
DOI: https://doi.org/10.1038/170208a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.