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Massive myelomatous ascites responsive to VAD chemotherapy and autologous stem cell transplantation

Bone Marrow Transplantation volume 24, pages 343–344 (1999)Cite this article

Abstract

Plasmacytic ascites is an infrequent complication of multiple myeloma. To date, only few cases have been reported with a very rapidly fatal course unresponsive to therapy. We describe a patient with plasmacytic ascites and quiescent multiple myeloma of 8 years of duration. Disease progression became apparent due to myelomatous ascites, unexplained fever, pancytopenia and bone marrow infiltration. This case showed a complete and long-lasting response after VAD chemotherapy followed by autologous PBSC transplantation. Ascites in association with MM may respond for lengthy periods to high-dose chemotherapy and ASCT.

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Authors and Affiliations

  1. Haematology Department, Hospital Universitario de la Princesa, Madrid, Spain

    A Alegre & JM Fernández-Rañada

  2. Clinica Ruber, Madrid, Spain

    C Martínez-Chamorro & JM Fernández-Rañada

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  1. A Alegre
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  2. C Martínez-Chamorro
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  3. JM Fernández-Rañada
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Alegre, A., Martínez-Chamorro, C. & Fernández-Rañada, J. Massive myelomatous ascites responsive to VAD chemotherapy and autologous stem cell transplantation. Bone Marrow Transplant 24, 343–344 (1999). https://doi.org/10.1038/sj.bmt.1701892

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  • DOI: https://doi.org/10.1038/sj.bmt.1701892

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